e1b1a in the levanthow to get insurance to pay for surgery

The Trans-Atlantic slave trade brought people to North America, Central America and South America including the Caribbean. E1b1a2 E1b1a2 is defined by the SNP mutation M329. E-V13's presence in this culture would explain why modern Iranians and Kurds possess E-V13, in addition to R1a-Z93 and R1b-Z2103. Since R1a-CTS1211 is not originally Germanic, it is likely that the Goths also brought a small but noticeable percentage of assimilated lineages from the Balkans, including E-V13 and J2b1 (I2a1b-CTS10228 would have come later from the East Slavic migrations from Ukraine during the Early Middle Ages, hence its absence from Italy, apart from a few coastal areas facing the Adriatic Sea). Because the West-Central African E1b1a data set is sufficiently large (n=516; eight groups), we would have expected to observe the E1b1a8a1a haplotype, if present at a frequency as low as 0.0058. Grard Lucotte et al. Mol Biol Evol 2011; 28: 12551269. All haplogroups within E1b1a were observed in the Bantu Homeland, West-Central Africa, East Africa and Ghana, whereas haplogroup E1b1a8a1a, although present in the Bantu Homeland and East Africa, was not observed in either Ghana or West-Central Africa. Late glacial migration of E-M78 to Mediterranean Europe It is still unclear when haplogroup E first entered Europe. Therefore, it is unlikely that the absence of this haplogroup is due to drift after the initial stage of expansion when only a small number of individuals may have been involved or is simply not being observed in the present study. Outside North Africa, M81 is far more frequent in parts of Iberia than anywhere else in Europe or the Near East. Perspective pg. The Harvey Y-DNA Genetic Project managed to retrace the ancestry and identify the Y-chromosomal haplogroup of William Harvey (1578 -1657), the first person to describe completely and in detail the systemic circulation and properties of blood being pumped to the body by the heart. The ancestral L485 SNP (along with several of its subclades) was very recently discovered. the migration of a small group of settlers carrying among whom one paternal lineage was much more common than any others. It's typical of all E1b1b haplogroups, but E1b1a has instead 438=11 and only 2% of E1b1a samples have 438=10. Therefore this lineage could actually have emerged a few centuries earlier, during the Phoenician/Carthaginian period. He is the nephew of screenwriter, film director and producer Francis Ford Coppola, who shares the same haplogroup. Because the Bantu languages on the eastern route are more homogeneous than those on the western route,11 it is reasonable to speculate that later expansions occurred mainly on the eastern route. You should learn them by the mutations because the letters change, the mutations don't. E1b1a used to be E3a, but always was E-M2. For comparison, the NRY haplotype diversity treating E1b1a as a single haplogroup ranged from 0.821 to 0.945, with the exception of Anuak who displayed a much lower diversity (h=0.516). We analyse frequencies of halpogroups and estimates of TMRCA to answer two questions: (a) Is there evidence of more than one expansion of paternal line ancestors of Bantu-speaking people living in present day sub-Saharan Africa? Last update February 2023 (famous members). As a consequence, this study makes an important contribution to filling the gap. In this study, we analyse, as did Alves et al,33 both UEP and short tandem repeat (STR) (in this study restricted to NRY) to show that geographic frequency distributions and the time to the most recent common ancestors (TMRCAs) of haplogroups, comprising haplogroup E1b1a in 43 sub-Saharan African groups (n=2757) with diverse linguistic affiliations (Supplementary Figure S1), reveal multiple waves of expansion from West Africa, with a late expansion along the eastern route but not the western. Provided by the Springer Nature SharedIt content-sharing initiative, European Journal of Human Genetics (Eur J Hum Genet) A back migration from Asia to sub-Saharan Africa is supported by high-resolution analysis of human Y-chromosome haplotypes. E1b1b lineages are closely linked to the diffusion of Afroasiatic languages. Annu Rev Anthropol 2001; 30: 181207. [69] This is the modal haplotype of STR markers that is common in carriers of E-U175. wiki: E-V22 Concentrated in Northeast Africa and the Near East. Y chromosomes traveling south: the cohen modal haplotype and the origins of the Lemba the Black Jews of Southern Africa. Also in favor of E1b1b-V22 is the fact that E1b1a occurs in 2% of Egyptians, while E1b1b-V22 occurs in 15% of north Egyptians, 5% in Egyptians from several oasis to the west of the Nile, and 4% in south Egyptians. Roewer L, Kayser M, de Knijff P et al. Since then, this marker (now defining the E1b1a haplogroup) has been typed in many groups across sub-Saharan Africa19, 26, 27, 28 and, without exception, all studies have shown that the majority of NRY types in Bantu-speaking groups belong to this haplogroup. Buccal swabs were collected from males >18 years old unrelated at the paternal grandfather level but otherwise randomly selected from 43 groups across sub-Saharan Africa (Supplementary Table S1, samples from Ghana, Nigeria and Cameroon were included in Veeramah et al (2010)35 and from South Africa in Thomas et al (2000)36). As a consequence it is consistent with a late, rapid expansion from south of the Grassfields of Cameroon that did not include expansion along the earlier western route. But in any case E-V13 was definitely not the major Neolithic European lineage it was once alleged to be. e1b1a is Bantu? Archaeological evidence suggests that the early expansion of proto-Bantu speakers was associated with pre-Iron Age farming technology and did not involve smelting metals.3 The first evidence of metallurgy south of the Sahara was found at Nok in Nigeria and is dated to no earlier than 2500 YBP.10 Therefore, it is possible that with the aid of the new technology, further expansions may have occurred after the first dispersal of farmers. Whilst E1b1a reaches its highest frequency of 81% in Senegal, only 1 of the 139 Senegalese that were tested showed M191/P86. The genetic structure and history of Africans and African Americans. If you are new to genetic genealogy, please check our Introduction to phylogenetics to understand how to read a phylogenetic tree. Thomas MG, Parfitt T, Weiss DA et al. However, since G2a is the only lineage that was consistently found in all Neolithic sites tested to date in Europe, the absence of Neolithic G2a lineages from Scandinavia and the Baltic implies that no Neolithic lineage survives there, and consequently E-V13 does not date from the Neolithic in the region. The Scottish Clan Colquhoun/Calhoun from Dunbartonshire belongs to the clade E-V13 > BY3880 > Y16729 > Y16721 > Y16733 according to the Calhoun Surname Project. A combination of the two scenarios could provide an even better explanation. All samples (96-well plates) were then placed on a thermocycler under the following conditions: denaturation at 95C for 5min, followed by 35 cycles of denaturation (95C) for 45s, annealing (see Supplementary Table S2 for annealing temperatures) for 45s and elongation (72C) for 45s. The final step of the PCR programme was a 7-min extension at 72C before a 30min hold at 4C. [25] Daba was of West African ancestry and carried haplogroups E1b1a-M4273 and L2c. Research Department of Genetics, The Centre for Genetic Anthropology, Evolution and Environment, University College London, London, UK, Naser Ansari Pour,Christopher A Plaster&Neil Bradman, You can also search for this author in (2007), such population movements changed the pre-existing population Y chromosomal diversity in Central, Southern, and Southeastern Africa, replacing the previous haplogroup frequencies in these areas with the now dominant E1b1a1 lineages. [25] Nana was of West African ancestry and carried haplogroup L2b3a. In . The samples were classified into groups primarily by cultural identity, first language spoken and then by place of collection. People and Disease. E-M78 and E-Z827 originated respectively at 20,000 years and 24,000 years. But that percentage very certainly increased after spending several centuries in Central and Southeast Europe and assimilating Proto-Slavs and Balkanic people before invading Italy. The TMRCA for each haplogroup-defining UEP (with at least 20 chromosomes) is presented in Table 3 along with regions and countries within which each haplogroup was observed. Visual representation of the distribution of E1b1a component haplogroups in sub-Saharan African groups with sample totals. Forensic Sci Int 2000; 114: 3143. Cereal farming may therefore trace its roots (literally) to the E1b1b tribes of the Mesolithic Levant. [25] Anika was of Sub-Saharan African ancestry and carried haplogroups E1b1a-CTS6126 and L2b1. The merits of this hypothesis is that it would explain why M81 is so much more common in the Maghreb, and particularly in Tunisia, than in Italy today. M310.1 itself dates from the Late Paleolithic and could have come to Italy via Anatolia and Greece any time between the Late Glacial period and the Iron Age, including with Neolithic farmers, the Minoans, or the Etruscans. What is even more surprising is that these subclades do not show any consistent geographic pattern. Our analysis of NRY from groups over a wide geographic area is consistent with both these conclusions. Indeed the distribution pattern and frequency of M81 matches much better the Phoenician maritime empire, with its origins in the Levant, and its dispersal along the cost of North Africa, but also Iberia, Sardinia and Sicily. [12], E1b1a1a1d is defined by a private marker M155. The box identifies the E1b1a clade, exclusively observed in population groups with recent African ancestry. Alexander's conquest of the Middle East would have taken Greek male lineages much further afield, perhaps as far as Afghanistan and Pakistan, although only at trace frequencies. A1b1b-M32 has a wide distribution including Khoisan speaking and East African populations, and scattered members on the Arabian Peninsula. The K257 and Y4970 branch emerged around 3000 BCE and is found in Iran, Armenia, Turkey, Russia, Greece, Italy and France, among others. Considering the Y haplogroup composition in our Dominican sample, we can note that the clades frequently observed in the Sahel are usually rare or absent. Where samples were ancestral for the four UEP markers, a further six to eleven UEPs (UEP1 and UEP2 kits: sY81, SRY4064, YAP, SRY10831, M13, M9, SRY465, M20, Tat, 92R7 and M17) were typed.38 NRY haplogroups were classified according to the nomenclature of the Y-Chromosome Consortium39 (Figure 1) and STR repeat sizes were assigned according to the nomenclature of Kayser et al.40 Additionally, the four E1b1a-specific UEPs were typed in 1820 samples, previously characterised as E1b1a in the TCGA database (published35, 36 and unpublished data), from the 35 non-Congo, sub-Saharan groups listed in Supplementary Table S1. Nat Genet 2000; 26: 358361. Genome Res 2008; 18: 830838. Haplogroup E-V68, also known as E1b1b1a, is a major human Y-chromosome DNA haplogroup found in North Africa, the Horn of Africa, Western Asia and Europe.It is a subclade of the larger and older haplogroup, known as E1b1b or E-M215 (also roughly equivalent to E-M35). (2002) states: "A possible explanation might be that haplotype 24 chromosomes [E-M2*] were already present across the Sudanese belt when the M191 mutation, which defines haplotype 22, arose in central western Africa. E1b1a and E1b1b-V22 tend to have lower values for this STR compared to other E1b1b haplogroups, but still the reported value is very rare in any of these haplogroups, and it looks like another suspicious STR value. (2021) indicates that Ramesses III and Unknown Man E, possibly Pentawere, carried haplogroup E1b1a. E1b1a1a1 is commonly defined by M180/P88. Author: Maciamo Hay. The Greeks remained in control of the Middle East until the Roman conquest, then regained influence over the region during the Byzantine period. 2018). These data are consistent with multiple expansion events southwards from West Africa. Ann Hum Genet 2002; 66: 369378. [19] Human leukocyte antigen alleles further confirm that the individuals were of Sub-Saharan African origin. Salas A, Richards M, De la FT et al. Am J Hum Genet 2000; 66: 674686. Note the resemblance between the distribution of E-M81 and the African admixture from the Dodecad project. Anthropology, archaeology, linguistics and, in recent decades, genetics have been used to elucidate some of the events and processes involved. M81 is especially common in western Iberia, notably Extremadura (15.5%), Andalusia (13.5%), southern Portugal (11%), the Canary Islands (11%), north-west Castille (10%) and Galicia (10%). The Wright Brothers, the inventors of the world's first successful airplane, belonged to haplogroup E-V13 (S7461 subclade). Dallas: SIL International, 2009. BMC Evol Biol 2009; 9: 80. Pereira L, Gusmao L, Alves C et al. At present the most consistent explanation is that E-V13 developed from E-M78 in Central or Eastern Europe during the Neolithic period, and was assimilated by the R1a and R1b Proto-Indo-Europeans around the time that they were leaving the Pontic Steppe to invade the rest of Europe. The African diaspora: mitochondrial DNA and the Atlantic slave trade. [10][11][12], At Taukome, in Botswana, an individual, dated to the Early Iron Age (1100 BP), carried haplogroups E1b1a1 (E-M2, E-Z1123) and L0d3b1. The haplogroup E1b1a8, defined by U175, has a TMRCA of only 18632163 YBP but a geographic distribution, excepting the Anuak of Ethiopia, which is equally extensive as that of E1b1a7. In the meantime, to ensure continued support, we are displaying the site without styles Thomas MG, Skorecki K, Ben Ami H, Parfitt T, Bradman N, Goldstein DB : Origins of old testament priests. Diamond J, Bellwood P : Farmers and their languages: the first expansions. [25] Kuto was of western Central African ancestry and carried haplogroups E1b1a-CTS2198 and L2a1a2. Ronny Decorte, a geneticist from the Catholic University of Leuven in Belgium, tested relatives of Adolf Hitler and determined that the Frher belonged to haplogroup E1b1b. You are using a browser version with limited support for CSS. One of them was E-M34 (notably Levantine clades like Y15558 and Z21421), which makes up about 15% of modern Lebanese Y-DNA, but was probably higher before the Greek, Roman, Arabic, Byzantine, medieval crusader and Ottoman occupations altered the local gene pool. More recently, based on over 1300 autosomal markers, Tishkoff et al13 showed that Bantu-speaking groups exhibit a considerable level of genetic similarity, a finding which is in good agreement with earlier studies mentioned above. [28][27] The ancestral sickle cell haplotype to modern haplotypes (e.g., Cameroon/Central African Republic and Benin/Senegal haplotypes) may have first arose in the ancestors of modern West Africans, bearing haplogroups E1b1a1-L485 and E1b1a1-U175 or their ancestral haplogroup E1b1a1-M4732. The Carthaginians founded cities in Spain, including Carthago Nova (the New Carthage, now Cartagena in Murcia), but also in Sardinia and Sicily, where M81 is the most common today within Italy. [29] Some may have migrated into and introduced the Senegal and Benin sickle cell haplotypes into Basra, Iraq, where both occur equally. The clade has been found at low frequencies in West Asia. Berniell-Lee G, Calafell F, Bosch E et al. The range and mean of sample sizes of the 43 groups are 25118 and 63, respectively. Ann Hum Genet 2001; 65: 439458. The EBSP impact on African demography has, over the past decade, also been studied by analysing paternal and maternal sex-specific genetic systems (non-recombining region of the Y chromosome (NRY) and mitochondrial DNA (mtDNA)). Was E-V13 a major lineage of Hallstatt Celts and Italics? ISSN 1018-4813 (print), Evidence from Y-chromosome analysis for a late exclusively eastern expansion of the Bantu-speaking people, Subdividing Y-chromosome haplogroup R1a1 reveals Norse Viking dispersal lineages in Britain, The role of matrilineality in shaping patterns of Y chromosome and mtDNA sequence variation in southwestern Angola, Autosomal genetics and Y-chromosome haplogroup L1b-M317 reveal Mount Lebanon Maronites as a persistently non-emigrating population, Y-chromosomal connection between Hungarians and geographically distant populations of the Ural Mountain region and West Siberia, A comprehensive portrait of Y-STR diversity of Indian populations and comparison with 129 worldwide populations, Origin and diffusion of human Y chromosome haplogroup J1-M267, The paternal and maternal genetic history of Vietnamese populations, North Asian population relationships in a global context, Early medieval genetic data from Ural region evaluated in the light of archaeological evidence of ancient Hungarians, Supplementary Tables S1-S2-S4 (DOC 141 kb), Distribution of paternal lineages in Mestizo populations throughout Mexico: an in silico study based on Y-STR haplotypes. E1B1B1 is of Levant origin, E1B1A is East African. [26] West Africans (e.g., Yoruba and Esan of Nigeria), bearing the Benin sickle cell haplotype, may have migrated through the northeastern region of Africa into the western region of Arabia. However, because each is, in effect, a single linked locus, interpreting observed differences among groups must be undertaken with a high level of caution. (2007) suggests that E-M78, E1b1b predominant subclade in Egypt, originated in "Northeastern Africa", with a corridor for bidirectional migrations between northeastern and eastern Africa (at least 2 episodes between 23.9-17.3 ky and 18.0-5.9 ky ago), trans-Mediterranean migrations directly from northern Africa to Europe (mainly in J Afr Hist 1995; 36: 173195. Am J Hum Genet 2002; 71: 10821111. Proto-Italics would have been a predominantly R1b-U152 tribe, but also carried a minority of E-V13, G2a-L140 (L13, L1264 and Z1816 subclades) and J2a1-L70 (PF5456 and Z2177 subclades). Thomas MG, Bradman N, Flinn HM : High throughput analysis of 10 microsatellite and 11 diallelic polymorphisms on the human Y-chromosome. The genetic data are thus in broad agreement with analysis based on linguistic studies, which suggests that the spread of Bantu languages is the consequence of successive dispersals and that a single large-scale migration by Bantu speakers is unlikely.3 It is also consistent with suggestions that differences between eastern and western Bantu languages are a consequence of expansion patterns.3 This interpretation suggests the absence of substantial male-mediated gene flow from East-Central Africa to West-Central Africa during the past millennium, because had it occurred, it would be expected that examples of haplogroup E1b1a8a1a would have been observed in the Congolese groups included in this study.

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